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Celexa causes less drug interactions, you should always let your doctor know what other medications you are taking. Depression associated with mood disorders. Citalopram is given as a single oral dose of 20 mg daily. As the elderly or those with co morbid illness. Citalopram is an antidepressant medication that affects neurotransmitters, the chemical transmitters within the brain. Celexa causes less drug interactions, you should always let your doctor know what other medications you are taking. You first start taking an MAO inhibitor.